C6243

Sigma

 

Monoclonal Anti-Cathepsin B antibody produced in mouse

~1.5 mg/mL, clone CB59-4B11, purified immunoglobulin, buffered aqueous solution

Description

Immunogenrecombinant human cathepsin B. The antibody epitope resides within the peptide sequence EPGYSP, which corresponds to amino acids 212-217 of human cathepsin B.
SpecificityThe antibody does not cross-react with the closely related lysosomal cysteine proteases cathespsins L, H, K, S, V, and W.
Physical formSolution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Properties

antibody formpurified immunoglobulin
cloneCB59-4B11 (monoclonal)
formbuffered aqueous solution
mol wtantigen mol wt ~25 kDa
species reactivityhuman, rat
concentration~1.5 mg/mL
application(s)immunoblotting1: 4-8 μg/mL using HCT-116 cells.
 immunohistochemistry: suitable
 indirect ELISA: suitable
isotypeIgG1
Gene Informationhuman ... CTSB(1508)
 rat ... CTSB(1508)
shipped indry ice
storage temp.−20°C

Related Products

Related productC6286, CathepsinĀ B from bovine spleen
 C8571, CathepsinĀ B from human liver

References

Cited Reference1. Di, Piazza., et al. J. Virol. 81, 4186-4198, (2007) Abstract